Sarcopenia in an overweight or obese patient is an adverse prognostic factor in pancreatic cancer

Benjamin H L Tan; Laura A Birdsell; Lisa Martin; Vickie E Baracos; Kenneth C H Fearon

doi:10.1158/1078-0432.CCR-09-1525

Sarcopenia in an overweight or obese patient is an adverse prognostic factor in pancreatic cancer

Benjamin H L Tan, Laura A Birdsell, Lisa Martin, Vickie E Baracos, Kenneth C H Fearon

Deanery of Clinical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

The average weight-losing pancreatic cancer patient undergoing palliative therapy is frequently overweight rather than underweight, and this can confound conventional measures used for risk stratification. The aim of this study was to evaluate if weight and body composition, specifically sarcopenia, assessed from diagnostic computed tomography (CT) scans, is of prognostic value in patients with pancreatic cancer. The nature and extent of tissue loss over subsequent months was also evaluated.

Original language	English
Pages (from-to)	6973-6979
Number of pages	7
Journal	Clinical Cancer Research
Volume	15
Issue number	22
DOIs	https://doi.org/10.1158/1078-0432.CCR-09-1525
Publication status	Published - 2009

Keywords

Aged
Body Composition
Body Weight
Female
Humans
Male
Middle Aged
Obesity
Overweight
Pancreatic Neoplasms
Prognosis
Risk
Sarcopenia
Tomography, X-Ray Computed
Treatment Outcome

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10.1158/1078-0432.CCR-09-1525

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title = "Sarcopenia in an overweight or obese patient is an adverse prognostic factor in pancreatic cancer",

abstract = "The average weight-losing pancreatic cancer patient undergoing palliative therapy is frequently overweight rather than underweight, and this can confound conventional measures used for risk stratification. The aim of this study was to evaluate if weight and body composition, specifically sarcopenia, assessed from diagnostic computed tomography (CT) scans, is of prognostic value in patients with pancreatic cancer. The nature and extent of tissue loss over subsequent months was also evaluated.",

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AU - Fearon, Kenneth C H

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KW - Pancreatic Neoplasms

KW - Prognosis

KW - Risk

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KW - Tomography, X-Ray Computed

KW - Treatment Outcome

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JO - Clinical Cancer Research

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SN - 1078-0432

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ER -

Sarcopenia in an overweight or obese patient is an adverse prognostic factor in pancreatic cancer

Abstract

Keywords

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