Scleroderma "en coup de sabre": pathological evidence of intracerebral inflammation

J Stone, A J Franks, J A Guthrie, M H Johnson, Jon Stone

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

Linear scleroderma "en coup de sabre" (LScs) is associated with neurological complications, the pathogenesis of which is uncertain. A 27 year old woman is reported on who developed epilepsy and focal neurological signs in association with LScs. Brain MRI demonstrated predominantly ipsilateral relapsing and remitting grey and white matter lesions. Analysis of CSF and pathology obtained at brain biopsy provides evidence of an inflammatory process which may be amenable to immunosuppressive treatment.

Original languageEnglish
Pages (from-to)382-5
Number of pages4
JournalJournal of Neurology, Neurosurgery & Psychiatry
Issue number3
Publication statusPublished - Mar 2001

Keywords / Materials (for Non-textual outputs)

  • Adult
  • Encephalitis
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Scleroderma, Localized


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