Seeing Is Believing: Myelin Dynamics in the Adult CNS

Matthew Swire*, Charles ffrench-Constant

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

Abstract / Description of output

Live imaging studies in mice show that adult-born oligodendrocytes and myelin are remarkably stable. Neural activity enhances oligodendrocyte integration, arguing that internode addition rather than alteration represents the mechanism for any experience-dependent cortical myelination changes that might underpin learning. Live imaging studies in mice show that adult-born oligodendrocytes and myelin are remarkably stable. Neural activity enhances oligodendrocyte integration, arguing that internode addition rather than alteration represents the mechanism for any experience-dependent cortical myelination changes that might underpin learning.

Original languageEnglish
Pages (from-to)684-686
Number of pages3
JournalNeuron
Volume98
Issue number4
DOIs
Publication statusE-pub ahead of print - 16 May 2018

Keywords / Materials (for Non-textual outputs)

  • aging
  • imaging
  • myelin
  • oligodendrocyte
  • plasticity

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