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Abstract
We have used a polymorphism dataset on introns and coding sequences of X-linked loci in Drosophila americana to estimate the strength of selection on codon usage and/or biased gene conversion (BGC), taking into account a recent population expansion detected by a maximum-likelihood method. Drosophila americana was previously thought to have a stable demographic history, so that this evidence for a recent population expansion means that previous estimates of selection need revision. There was evidence for natural selection or BGC favouring GC over AT variants in introns, which is stronger for GC-rich than GC-poor introns. By comparing introns and coding sequences, we found evidence for selection on codon usage bias, which is much stronger than the forces acting on GC versus AT basepairs in introns.
Original language | English |
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Pages (from-to) | 82-85 |
Number of pages | 4 |
Journal | Biology letters |
Volume | 8 |
Issue number | 1 |
DOIs | |
Publication status | Published - 23 Feb 2012 |
Keywords
- Drosophila americana
- codon usage
- biased gene conversion
- population expansion
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Dive into the research topics of 'Selection on codon usage and base composition in Drosophila americana'. Together they form a unique fingerprint.Projects
- 1 Finished
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The evolutionary genomics of X chromosomes
Charlesworth, B., Betancourt, A. J. & Marion de Proce, S.
5/12/08 → 4/03/12
Project: Research