Self-Reported Quality of Life in a Scottish First Episode Psychosis Cohort: Associations with Symptomatology and Premorbid Adjustment

Angus Macbeth*, Andrew Gumley, Matthias Schwannauer, R. Fisher

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


There is increased interest in quality of life as a clinically relevant factor in adjustment to, and recovery from first episode psychosis. Given the subjective nature of quality of life it is proposed that this variable may be associated with compromised functioning prior to the onset of psychosis, and may also have an impact on an individual’s adjustment to psychosis after treatment is initiated.
The current study aims to explore associations between subjective quality of life, symptomatology, premorbid adjustment, duration of untreated psychosis (DUP) and engagement with services after onset of treatment.
A cross sectional cohort of Scottish individuals undergoing treatment for First Episode Psychosis (FEP) were characterised in terms of psychotic symptomatology, premorbid adjustment, DUP, and service engagement. Self reported quality of life (sQoL) was measured using the WHOQOL-BREF, allowing for the measurement of physical, psychological, social relational and environmental aspects of quality of life.
Higher scores for subjective quality of life components were associated with better premorbid adjustment, lower positive psychotic symptoms, lower negative symptoms and less cognitive disorganization. Childhood premorbid adjustment predicted both physical and social relationship QoL.
Subjective Quality of life domains differ in their associations with clinical and premorbid factors. The role of elationship between premorbid adjustment as a predictor ofand quality of life requires further exploration in FEP.
Original languageEnglish
Pages (from-to)53-60
Number of pages8
JournalEarly Intervention in Psychiatry
Issue number1
Early online date22 Aug 2013
Publication statusPublished - 1 Jan 2015


  • Premorbid adjustment
  • Psychotic disorder
  • Quality of life

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