Prostaglandin E(2) (PGE(2)) has been shown to modulate angiogenesis and tumour progression via the E-series prostanoid-2 (EP2) receptor. Endometrial adenocarcinomas may be exposed to endogenous PGE(2) and exogenous PGE(2), present at high concentration in seminal plasma.
- Endometrial carcinoma
- E-series prostanoid receptor 2
- Fibroblast Growth Factor 2
- SEMINAL PLASMA