Sensing H+ with conventional neural probes

T. Trantidou*, T. Prodromakis, V. Tsiligkiridis, Y. C. Chang, C. Toumazou

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

In this paper, we demonstrate a technique for transforming commercially available neural probes used for electrical recordings, into chemical sensing devices for detection of ionic concentrations in electrolytes, with particular emphasis to pH. This transformation requires a single post-processing step to incorporate a thin indium tin oxide membrane for sensing H+. Measured results indicate a chemical sensitivity of 28 mV/pH, and relatively low leakage currents (2-10 nA) and drifts (1-10 mV/h). The proposed sensing device demonstrates the possibility of a low-cost implementation that can be reusable and thus versatile, with potential applications in real-time extracellular but mainly intracellular chemical monitoring.

Original languageEnglish
Article number223506
JournalApplied Physics Letters
Volume102
Issue number22
DOIs
Publication statusPublished - 4 Jun 2013

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