Sequencing, tissue distribution and chromosomal assignment of a novel ubiquitin-specific protease USP23

T S Smith, C Southan

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

We have identified human and mouse cDNAs encoding a novel ubiquitin-specific protease designated USP23. Both cDNAs encode a 62-kDa protein containing the highly conserved His and Cys domains characteristic of the C19 cysteine protease family of ubiquitin-specific processing proteases (UCH-2). Human tissue Northern blots revealed USP23 to be ubiquitously expressed, whereas USP12, its closest human paralogue, displayed a more restricted expression pattern. The human USP23 gene mapped to chromosome 1q22.

Original languageEnglish
Pages (from-to)184-8
Number of pages5
JournalBBA - Bioenergetics
Volume1490
Issue number1-2
Publication statusPublished - 31 Jan 2000

Keywords / Materials (for Non-textual outputs)

  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Carbon-Nitrogen Lyases
  • Chromosome Mapping
  • Cysteine Endopeptidases
  • Gene Expression
  • Humans
  • Mice
  • Molecular Sequence Data
  • Sequence Alignment
  • Sequence Homology
  • Ubiquitin Thiolesterase

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