Serology-based diagnostics for the control of bovine neosporosis

Stefano Guido; Frank Katzer; Ian Nanjiani; Elspeth Milne; Elisabeth A. Innes

doi:10.1016/j.pt.2015.11.014

Serology-based diagnostics for the control of bovine neosporosis

Stefano Guido, Frank Katzer, Ian Nanjiani, Elspeth Milne, Elisabeth A. Innes

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

The protozoan Neospora caninum is a primary infectious cause of abortion in cattle that causes significant economic losses worldwide. As effective vaccines and licensed pharmacological treatments are currently unavailable, control measures rely on biosecurity and management practice. Serological diagnosis plays a crucial role in the identification of infected animals and a number of tests have been developed. However, due to the particular dynamics of the host-parasite interaction and to the characteristics of the currently used diagnostic tools, a proportion of infected cattle may not be reliably identified and can potentially undermine efforts towards the control of bovine neosporosis. Here, current diagnostic methods for N. caninum infection in cattle and the advancements required to support effective control strategies are discussed.

Original language	English
Journal	Trends in Parasitology
Early online date	17 Dec 2015
DOIs	https://doi.org/10.1016/j.pt.2015.11.014
Publication status	E-pub ahead of print - 17 Dec 2015

Access to Document

10.1016/j.pt.2015.11.014

Serology-based diagnostics for the control of bovine neosporosisAccepted author manuscript, 42.3 KB
Fig 1Accepted author manuscript, 100 KB
Fig 2Accepted author manuscript, 1.5 MB
Table 1Accepted author manuscript, 16.7 KB
Box 1Accepted author manuscript, 15.6 KB
TrendsAccepted author manuscript, 15.4 KB
QuestionsAccepted author manuscript, 16.9 KB

Cite this

@article{e9fa4ad043d84828a2a5c0a87d6ce15d,

title = "Serology-based diagnostics for the control of bovine neosporosis",

abstract = "The protozoan Neospora caninum is a primary infectious cause of abortion in cattle that causes significant economic losses worldwide. As effective vaccines and licensed pharmacological treatments are currently unavailable, control measures rely on biosecurity and management practice. Serological diagnosis plays a crucial role in the identification of infected animals and a number of tests have been developed. However, due to the particular dynamics of the host-parasite interaction and to the characteristics of the currently used diagnostic tools, a proportion of infected cattle may not be reliably identified and can potentially undermine efforts towards the control of bovine neosporosis. Here, current diagnostic methods for N. caninum infection in cattle and the advancements required to support effective control strategies are discussed.",

author = "Stefano Guido and Frank Katzer and Ian Nanjiani and Elspeth Milne and Innes, {Elisabeth A.}",

year = "2015",

month = dec,

day = "17",

doi = "10.1016/j.pt.2015.11.014",

language = "English",

journal = "Trends in Parasitology",

issn = "1471-4922",

publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Serology-based diagnostics for the control of bovine neosporosis

AU - Guido, Stefano

AU - Katzer, Frank

AU - Nanjiani, Ian

AU - Milne, Elspeth

AU - Innes, Elisabeth A.

PY - 2015/12/17

Y1 - 2015/12/17

N2 - The protozoan Neospora caninum is a primary infectious cause of abortion in cattle that causes significant economic losses worldwide. As effective vaccines and licensed pharmacological treatments are currently unavailable, control measures rely on biosecurity and management practice. Serological diagnosis plays a crucial role in the identification of infected animals and a number of tests have been developed. However, due to the particular dynamics of the host-parasite interaction and to the characteristics of the currently used diagnostic tools, a proportion of infected cattle may not be reliably identified and can potentially undermine efforts towards the control of bovine neosporosis. Here, current diagnostic methods for N. caninum infection in cattle and the advancements required to support effective control strategies are discussed.

AB - The protozoan Neospora caninum is a primary infectious cause of abortion in cattle that causes significant economic losses worldwide. As effective vaccines and licensed pharmacological treatments are currently unavailable, control measures rely on biosecurity and management practice. Serological diagnosis plays a crucial role in the identification of infected animals and a number of tests have been developed. However, due to the particular dynamics of the host-parasite interaction and to the characteristics of the currently used diagnostic tools, a proportion of infected cattle may not be reliably identified and can potentially undermine efforts towards the control of bovine neosporosis. Here, current diagnostic methods for N. caninum infection in cattle and the advancements required to support effective control strategies are discussed.

U2 - 10.1016/j.pt.2015.11.014

DO - 10.1016/j.pt.2015.11.014

M3 - Article

SN - 1471-4922

JO - Trends in Parasitology

JF - Trends in Parasitology

ER -

Serology-based diagnostics for the control of bovine neosporosis

Abstract / Description of output

Access to Document

Fingerprint

Cite this