Serum IL-8 and MCP-1 concentration do not identify patients with enlarging contusions after traumatic brain injury

Jonathan Rhodes, John Sharkey, Peter Andrews

Research output: Contribution to journalArticlepeer-review

Abstract

Cerebral contusions contain numerous leukocytes, and a temporal relationship exists among cerebral chemokine expression, leukocyte recruitment, and contusion enlargement. This would suggest a role for chemokines in contusion development. However, it has not been established if serum concentrations of chemokines such as interleukin-8 (IL-8) or monocyte chemoattractant protein-1 (MCP-1) change with contusion enlargement.
Original languageEnglish
Pages (from-to)1591-7; discussion 1598
JournalJournal of Trauma: Injury, Infection, and Critical Care
Volume66
Issue number6
DOIs
Publication statusPublished - Jun 2009

Keywords

  • Young Adult
  • Chemokine CCL2
  • Humans
  • Adult
  • Disease Progression
  • Aged
  • Middle Aged
  • Interleukin-8
  • Brain Injuries
  • Male
  • Female

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