Serum interleukin 6 (IL-6) - effect of surgery and under-nutrition

A M Cruickshank, G Jennings, K H Fearon, M Elia, A Shenkin

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

We aimed to investigate the role of IL-6 as a mediator of the acute phase response (APR) in man; to assess the effect of under-nutrition on serum/plasma IL-6 levels; and to assess the value of IL-6 as a prognostic indicator by measuring IL-6 in timed venous samples taken from surgical patients and from protein deficient and control rats post-turpentine injections. Serum IL-6 rose in all surgical patients within 2-4h of incision. Peak levels differed among the groups and correlated significanlly with duration of surgery (r = 0.75, p
Original languageEnglish
Pages (from-to)65-9
Number of pages5
JournalClinical Nutrition
Volume10 Suppl
Publication statusPublished - 1991


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