Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

Stuart W Naylor; Allen Flockhart; Pablo Nart; David G E Smith; John Huntley; David L Gally; J Christopher Low

doi:10.1128/AEM.02670-06

Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

Stuart W Naylor, Allen Flockhart, Pablo Nart, David G E Smith, John Huntley, David L Gally, J Christopher Low

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

Original language	English
Pages (from-to)	3765-3767
Number of pages	3
Journal	Applied and Environmental Microbiology
Volume	73
Issue number	11
DOIs	https://doi.org/10.1128/AEM.02670-06
Publication status	Published - Jun 2007

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10.1128/AEM.02670-06

Shedding of Escherichia coli O157 H7 in Calves Is Reduced by Prior Colonization with the Homologous Strain
Copyright © 2007, American Society for Microbiology
Final published version, 109 KB

http://aem.asm.org/content/73/11/3765

The molecular basis to Escherichia coli O157:H7 colonisation of the terminal rectum in cattle
Gally, D.
BBSRC
1/12/03 → 31/01/07
Project: Research

Cite this

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title = "Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain",

abstract = "Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.",

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AU - Flockhart, Allen

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AU - Smith, David G E

AU - Huntley, John

AU - Gally, David L

AU - Low, J Christopher

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AB - Enterohemorrhagic Escherichia coli O157:H7 has a natural reservoir in the intestinal tracts of cattle. Colonization is asymptomatic and transient, but it is not clear if protective immunity is induced. This study demonstrates that prior colonization induces humoral immune responses to bacterial antigens and reduces bacterial shedding after experimental challenge with the homologous strain.

U2 - 10.1128/AEM.02670-06

DO - 10.1128/AEM.02670-06

M3 - Article

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VL - 73

SP - 3765

EP - 3767

JO - Applied and Environmental Microbiology

JF - Applied and Environmental Microbiology

SN - 0099-2240

IS - 11

ER -

Shedding of Escherichia coli O157:H7 in calves is reduced by prior colonization with the homologous strain

Abstract

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The molecular basis to Escherichia coli O157:H7 colonisation of the terminal rectum in cattle

Cite this