Should patients with acute coronary disease be stratified for management according to their risk?: Derivation, external validation and outcomes using the updated GRACE risk score

Keith A A Fox; Gordon Fitzgerald; Etienne Puymirat; Wei Huang; Kathryn Carruthers; Tabassome Simon; Pierre Coste; Jacques Monsegu; Philippe Gabriel Steg; Nicolas Danchin; Fred Anderson

doi:10.1136/bmjopen-2013-004425

Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score

Keith A A Fox, Gordon Fitzgerald, Etienne Puymirat, Wei Huang, Kathryn Carruthers, Tabassome Simon, Pierre Coste, Jacques Monsegu, Philippe Gabriel Steg, Nicolas Danchin, Fred Anderson

Research output: Contribution to journal › Article › peer-review

Abstract / Description of output

Risk scores are recommended in guidelines to facilitate the management of patients who present with acute coronary syndromes (ACS). Internationally, such scores are not systematically used because they are not easy to apply and some risk indicators are not available at first presentation. We aimed to derive and externally validate a more accurate version of the Global Registry of Acute Coronary Events (GRACE) risk score for predicting the risk of death or death/myocardial infarction (MI) both acutely and over the longer term. The risk score was designed to be suitable for acute and emergency clinical settings and usable in electronic devices.

Original language	English
Pages (from-to)	e004425
Journal	BMJ Open
Volume	4
Issue number	2
DOIs	https://doi.org/10.1136/bmjopen-2013-004425
Publication status	Published - 2014

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10.1136/bmjopen-2013-004425

Should patients with acute coronary disease be stratified for management according to their risk
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http://bmjopen.bmj.com/content/4/2/e004425

Phenotypic and genetic markers of risk in acute coronary syndromes: Long term follow up in South East Scotland using Scottish Records linkage
Fox, K.
UK central government bodies/local authorities, health and hospital authorities
1/10/09 → 28/02/11
Project: Research

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Fox, K. A. A., Fitzgerald, G., Puymirat, E., Huang, W., Carruthers, K., Simon, T., Coste, P., Monsegu, J., Gabriel Steg, P., Danchin, N., & Anderson, F. (2014). Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score. BMJ Open, 4(2), e004425. https://doi.org/10.1136/bmjopen-2013-004425

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abstract = "Risk scores are recommended in guidelines to facilitate the management of patients who present with acute coronary syndromes (ACS). Internationally, such scores are not systematically used because they are not easy to apply and some risk indicators are not available at first presentation. We aimed to derive and externally validate a more accurate version of the Global Registry of Acute Coronary Events (GRACE) risk score for predicting the risk of death or death/myocardial infarction (MI) both acutely and over the longer term. The risk score was designed to be suitable for acute and emergency clinical settings and usable in electronic devices.",

author = "Fox, {Keith A A} and Gordon Fitzgerald and Etienne Puymirat and Wei Huang and Kathryn Carruthers and Tabassome Simon and Pierre Coste and Jacques Monsegu and {Gabriel Steg}, Philippe and Nicolas Danchin and Fred Anderson",

year = "2014",

doi = "10.1136/bmjopen-2013-004425",

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Fox, KAA, Fitzgerald, G, Puymirat, E, Huang, W, Carruthers, K, Simon, T, Coste, P, Monsegu, J, Gabriel Steg, P, Danchin, N & Anderson, F 2014, 'Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score', BMJ Open, vol. 4, no. 2, pp. e004425. https://doi.org/10.1136/bmjopen-2013-004425

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AU - Fox, Keith A A

AU - Fitzgerald, Gordon

AU - Puymirat, Etienne

AU - Huang, Wei

AU - Carruthers, Kathryn

AU - Simon, Tabassome

AU - Coste, Pierre

AU - Monsegu, Jacques

AU - Gabriel Steg, Philippe

AU - Danchin, Nicolas

AU - Anderson, Fred

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AB - Risk scores are recommended in guidelines to facilitate the management of patients who present with acute coronary syndromes (ACS). Internationally, such scores are not systematically used because they are not easy to apply and some risk indicators are not available at first presentation. We aimed to derive and externally validate a more accurate version of the Global Registry of Acute Coronary Events (GRACE) risk score for predicting the risk of death or death/myocardial infarction (MI) both acutely and over the longer term. The risk score was designed to be suitable for acute and emergency clinical settings and usable in electronic devices.

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DO - 10.1136/bmjopen-2013-004425

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JO - BMJ Open

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Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score

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Phenotypic and genetic markers of risk in acute coronary syndromes: Long term follow up in South East Scotland using Scottish Records linkage

Cite this