Shuttle Catalysis—New Strategies in Organic Synthesis

Benjamin N. Bhawal, Bill Morandi*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Shuttle catalysis has recently emerged as a powerful new concept that provides a platform for performing both functionalization and defunctionalization reactions. In this concept article, applications of shuttle catalysis as a novel strategy in organic synthesis are discussed. This includes using forward shuttle catalysis reactions for challenging bond-forming processes that avoid the use of hazardous chemicals. Shuttle catalysis also facilitates the transfer of reactive functionality as a route to procure a broad range of compounds using one simple procedure. Reverse shuttle catalysis reactions are also discussed as a method for the valorization of biomass and waste materials. Another area of interest, shuttle-catalysis-assisted reactions, wherein the transfer of a small molecule is utilized in a catalytic cycle, is also described. Possible future directions in this exciting new field are also suggested.

Original languageEnglish
Pages (from-to)12004-12013
Number of pages10
JournalChemistry - A European Journal
Volume23
Issue number50
Early online date15 Mar 2017
DOIs
Publication statusPublished - 7 Sep 2017

Keywords

  • alkenes
  • defunctionalization
  • functionalization
  • reversible
  • shuttle catalysis

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