Simulating isolated populations to identify emerging genetic structure

C Hosking, Robert Ogden, Helen Senn

Research output: Working paper


Conservation efforts are often informed by measures of genetic structure within or between isolated populations. We have established a simulation approach to investigate how isolated or captive populations can display misleading (i.e recently acquired) genetic structure as a result of genetic drift. We utilized a combination of softwares to generate isolated population genetic datasets that allow interrogation of emerging genetic structure under a range of conditions. We have developed a new statistic, S, to describe the extent of differentiation due to genetic drift between two isolated populations within the clustering software, STRUCTURE.
Original languageEnglish
PublisherbioRxiv, at Cold Spring Harbor Laboratory
Publication statusE-pub ahead of print - 25 Nov 2019

Publication series

Publishercold spring harbor


  • Drift
  • Founder effects
  • Captivity
  • Inbreeding
  • Ex-situ


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