siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity

Mark S Duxbury; Hiromichi Ito; Michael J Zinner; Stanley W Ashley; Edward E Whang

doi:10.1016/j.jamcollsurg.2004.01.037

siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity

Mark S Duxbury
, Hiromichi Ito
, Michael J Zinner
, Stanley W Ashley
, Edward E Whang

School of Regeneration and Repair

Research output: Contribution to journal › Article › peer-review

Abstract

The c-Src tyrosine kinase is a determinant of malignant cellular behavior in a variety of human cancers. We sought to determine the effect of suppressing c-Src expression on pancreatic adenocarcinoma chemosensitivity to gemcitabine.

Original language	English
Pages (from-to)	953-9
Number of pages	7
Journal	Journal of the American College of Surgeons
Volume	198
Issue number	6
DOIs	https://doi.org/10.1016/j.jamcollsurg.2004.01.037
Publication status	Published - 2004

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10.1016/j.jamcollsurg.2004.01.037

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@article{60319a81b1c143e2b81bf2e3ef21c6a8,

title = "siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity",

abstract = "The c-Src tyrosine kinase is a determinant of malignant cellular behavior in a variety of human cancers. We sought to determine the effect of suppressing c-Src expression on pancreatic adenocarcinoma chemosensitivity to gemcitabine.",

author = "Duxbury, \{Mark S\} and Hiromichi Ito and Zinner, \{Michael J\} and Ashley, \{Stanley W\} and Whang, \{Edward E\}",

year = "2004",

doi = "10.1016/j.jamcollsurg.2004.01.037",

language = "English",

volume = "198",

pages = "953--9",

journal = "Journal of the American College of Surgeons",

issn = "1072-7515",

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}

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T1 - siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity

AU - Duxbury, Mark S

AU - Ito, Hiromichi

AU - Zinner, Michael J

AU - Ashley, Stanley W

AU - Whang, Edward E

PY - 2004

Y1 - 2004

N2 - The c-Src tyrosine kinase is a determinant of malignant cellular behavior in a variety of human cancers. We sought to determine the effect of suppressing c-Src expression on pancreatic adenocarcinoma chemosensitivity to gemcitabine.

AB - The c-Src tyrosine kinase is a determinant of malignant cellular behavior in a variety of human cancers. We sought to determine the effect of suppressing c-Src expression on pancreatic adenocarcinoma chemosensitivity to gemcitabine.

U2 - 10.1016/j.jamcollsurg.2004.01.037

DO - 10.1016/j.jamcollsurg.2004.01.037

M3 - Article

C2 - 15194078

SN - 1072-7515

VL - 198

SP - 953

EP - 959

JO - Journal of the American College of Surgeons

JF - Journal of the American College of Surgeons

IS - 6

ER -

siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity

Abstract

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