Sleep-related motor and behavioral disorders: Recent advances and new entities

David P Breen, Birgit Högl, Alfonso Fasano, Claudia Trenkwalder, Anthony E Lang

Research output: Contribution to journalReview articlepeer-review

Abstract / Description of output

Patients with sleep-related motor and behavioral disorders present to a variety of subspecialty clinics (neurology, sleep medicine, respiratory medicine, psychiatry). Diagnosing these disorders can be difficult, and sometimes they have a significant impact on quality of life. Alongside a number of common and well-recognized conditions, several new disease entities have been described in recent years that present with abnormal nocturnal motor phenomena (such as ADCY5-associated disease and anti-IgLON5 disease). Our understanding of the neural basis and prognostic significance of other sleep-related disorders has also grown, particularly rapid eye movement sleep behavior disorder. This review (along with a collection of previously unpublished videos) is intended to aid in the recognition and treatment of these patients. The recent change in terminology from nocturnal frontal lobe epilepsy to sleep-related hypermotor epilepsy is also discussed. © 2018 International Parkinson and Movement Disorder Society.

Original languageEnglish
Pages (from-to)1042-1055
Number of pages14
JournalMovement Disorders
Volume33
Issue number7
Early online date14 May 2018
DOIs
Publication statusPublished - Jul 2018

Keywords / Materials (for Non-textual outputs)

  • Humans
  • Mental Disorders/diagnosis
  • Movement Disorders/diagnosis
  • Sleep Wake Disorders/complications

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