Small Intestinal Ganglioneuromatosis in a Dog

J. K. Paris, I. A. McCandlish, T. Schwarz, J. W. Simpson, S. H. Smith

Research output: Contribution to journalArticlepeer-review

Abstract

A 9-year-old female neutered collie-cross dog was presented with a 2-month history of persistent diarrhoea, weight loss and intermittent vomiting. Abdominal ultrasonography revealed one loop of jejunum with a markedly thickened and multifocally hyperechoic wall, without loss of wall layering. Laparotomies were performed for biopsy and resection of affected intestine. Histopathological examination revealed small intestinal ganglioneuromatosis (GN). The dog recovered well from surgery and the diarrhoea resolved. Eleven months later the dog has gained weight and remains asymptomatic. This is the first report of small intestinal GN affecting a mature dog, in which pathology was localized to the mucosal lamina propria and surgical treatment resulted in a successful outcome.
Original languageEnglish
Pages (from-to)323-328
JournalJournal of Comparative Pathology
Volume148
Issue number4
Early online date29 Aug 2012
DOIs
Publication statusPublished - 2012

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