Small variable segments constitute a major type of diversity of bacterial genomes at the species level

Fabrice Touzain, Erick Denamur, Claudine Médigue, Valérie Barbe, Meriem El Karoui, Marie-Agnès Petit

Research output: Contribution to journalArticlepeer-review

Abstract

Analysis of large scale diversity in bacterial genomes has mainly focused on elements such as pathogenicity islands, or more generally, genomic islands. These comprise numerous genes and confer important phenotypes, which are present or absent depending on strains. We report that despite this widely accepted notion, most diversity at the species level is composed of much smaller DNA segments, 20 to 500 bp in size, which we call microdiversity.
Original languageEnglish
Article numberR45
JournalGenome Biology
Volume11
Issue number4
DOIs
Publication statusPublished - 2010

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