Solid-phase synthesis of BODIPY dyes and development of an immunoglobulin fluorescent sensor

Marc Vendrell, Gaddamanugu Gopi Krishna, Krishna Kanta Ghosh, Duanting Zhai, Jun-Seok Lee, Qing Zhu, Yin Hoe Yau, Susana Geifman Shochat, Hyori Kim, Junho Chung, Young-Tae Chang*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The diversification of the BODIPY scaffold has been hindered by its controversial adaptability to solid-phase chemistry. Herein we report the first solid-phase synthesis of a BODIPY library in high purities. We screened the library against a set of proteins, identified an immunoglobulin fluorescent sensor (Ig Orange) and confirmed its binding by SPR experiments.

Original languageEnglish
Pages (from-to)8424-8426
Number of pages3
JournalChemical Communications
Volume47
Issue number29
DOIs
Publication statusPublished - 2011

Keywords / Materials (for Non-textual outputs)

  • COMBINATORIAL SYNTHESIS
  • CYANINE DYES
  • FUNCTIONALIZATION
  • DERIVATIVES
  • LIBRARY
  • CHEMISTRY
  • DESIGN
  • PROBE
  • BORON

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