Solvable senescence model showing a mortality plateau

J B Coe, Y Mao, M E Cates

Research output: Contribution to journalArticlepeer-review

Abstract

We present some analytic results for the steady states of the Penna model of senescence, generalized to allow genetically identical individuals to die at different ages via an arbitrary survival function. Modeling this with a Fermi function (of modest width) we obtain a clear mortality plateau late in life: something that has so far eluded explanation within such mutation accumulation models. This suggests that factors causing variable mortality within genetically identical subpopulations, which include environmental effects, may be essential to understanding the mortality plateau seen in many real species.

Original languageEnglish
Article number288103
Pages (from-to)-
Number of pages4
JournalPhysical Review Letters
Volume89
Issue number28
DOIs
Publication statusPublished - 31 Dec 2002

Cite this