Abstract
Cloning by nuclear transfer from adult somatic cells is a remarkable demonstration of developmental plasticity. When a nucleus is placed in oocyte cytoplasm, the changes in chromatin structure that govern differentiation can be reversed, and the nucleus can be made to control development to term.
Original language | English |
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Pages (from-to) | 583-6 |
Number of pages | 4 |
Journal | Nature |
Volume | 419 |
Issue number | 6907 |
DOIs | |
Publication status | Published - 10 Oct 2002 |
Keywords / Materials (for Non-textual outputs)
- Animals
- Cattle
- Cell Cycle
- Cell Differentiation
- Cloning, Organism
- Embryonic and Fetal Development
- Fetal Death
- Forecasting
- Gene Expression Regulation, Developmental
- Goats
- Mice
- Nuclear Transfer Techniques
- Oocytes
- Ploidies
- Sheep
- Swine
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Somatic Cell Nuclear Transfer (Cloning) Efficiency
Wilmut, I. (Creator) & Paterson, L. A. (Creator), Edinburgh DataShare, Jul 2002
DOI: 10.7488/ds/312, http://www.nature.com/nature/journal/v419/n6907/full/nature01079.html
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