Some principles and practices of genetic biobanking studies

A. K. Macleod, David Liewald, M. M. McGilchrist, Andrew Morris, S. M. Kerr, D. J. Porteous

Research output: Contribution to journalArticlepeer-review

Abstract

Genetic biobanking studies are becoming increasingly common as researchers recognise the need for large samples to identify the genetic basis of susceptibility to complex disease. In the present review, the authors give a brief overview of some of the issues that should be considered when implementing such a large-scale project, from study design to sample management, data coding and storage to the statistical analysis and engagement with the public. Specific solutions to these issues are presented, as implemented in the Generation Scotland projects, but the general principles outlined are relevant to any biobanking study.
Original languageEnglish
Pages (from-to)419-425
Number of pages7
JournalEuropean Respiratory Journal
Volume33
Issue number2
DOIs
Publication statusPublished - Feb 2009

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