Projects per year
Abstract / Description of output
Models of chemical kinetics that incorporate both stochasticity and diffusion are an increasingly common tool for studying biology. The variety of competing models is vast, but two stand out by virtue of their popularity: the reaction–diffusion master equation and Brownian dynamics. In this review, we critically address a number of open questions surrounding these models: How can they be justified physically? How do they relate to each other? How do they fit into the wider landscape of chemical models, ranging from the rate equations to molecular dynamics? This review assumes no prior knowledge of modelling chemical kinetics and should be accessible to a wide range of readers.
Original language | English |
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Number of pages | 50 |
Journal | Bulletin of Mathematical Biology |
Early online date | 21 May 2018 |
DOIs | |
Publication status | E-pub ahead of print - 21 May 2018 |
Keywords / Materials (for Non-textual outputs)
- Brownian dynamics
- Reaction–diffusion master equation
- Spatial models
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Dive into the research topics of 'Spatial Stochastic Intracellular Kinetics: A Review of Modelling Approaches'. Together they form a unique fingerprint.Projects
- 2 Finished
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Pushing the frontiers of stochastic modelling in biology:intrinsic noise in non-dilute conditions
17/03/14 → 30/09/16
Project: Research
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EASTBIO: EASTBIO East of Scotland BioScience Doctoral Training Partnership studentship - Research Training Grant BB/J01446X/1
Smith, S.
1/09/12 → 30/09/18
Project: Other (Non-Funded/Miscellaneous)