We analyzed the frequency spectrum of magnetoencephalogram (MEG) background activity in 16 bipolar disorder (BD) patients and 24 age-matched healthy control. Median frequency (MF), spectral entropy (SpEn), and relative power in delta (RPδ), theta (RPθ), alpha (RPα), beta (RPβ), and gamma (RPγ) bands were computed for all 148 MEG channels. Significant differences between the two groups were found in the average level of MF, RPδ, and RPθ in the posterior region of the scalp. Moreover, the MF, SpEn, RPδ, and RPβ values of BD patients had a different dependence on age as compared with the results of control subjects, which may suggest that BD affects how the brain activity develops with age. We conclude that the spectral analysis of the background MEG in BD patients may give insights into how this condition affects the brain activity.
|Title of host publication||Proceedings of the 36th Annual International Conference of the IEEE Engineering in Medicince and Biology Society|
|Publisher||IEEE Engineering in Medicine and Biology Society|
|Publication status||Published - 28 Aug 2014|
|Event||36th Annual International Conference of the IEEE Engineering in Medicince and Biology Society - Chicago, United States|
Duration: 27 Aug 2014 → 30 Aug 2014
|Conference||36th Annual International Conference of the IEEE Engineering in Medicince and Biology Society|
|Period||27/08/14 → 30/08/14|