Spectral Analysis of Resting State Magnetoencephalogram Activity in Patients with Bipolar Disorder

Ali H. Al-Timemy, Alberto Fernandez, Javier Escudero

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We analyzed the frequency spectrum of magnetoencephalogram (MEG) background activity in 16 bipolar disorder (BD) patients and 24 age-matched healthy control. Median frequency (MF), spectral entropy (SpEn), and relative power in delta (RPδ), theta (RPθ), alpha (RPα), beta (RPβ), and gamma (RPγ) bands were computed for all 148 MEG channels. Significant differences between the two groups were found in the average level of MF, RPδ, and RPθ in the posterior region of the scalp. Moreover, the MF, SpEn, RPδ, and RPβ values of BD patients had a different dependence on age as compared with the results of control subjects, which may suggest that BD affects how the brain activity develops with age. We conclude that the spectral analysis of the background MEG in BD patients may give insights into how this condition affects the brain activity.
Original languageEnglish
Title of host publicationProceedings of the 36th Annual International Conference of the IEEE Engineering in Medicince and Biology Society
PublisherIEEE Engineering in Medicine and Biology Society
Pages2197-2200
Publication statusPublished - 28 Aug 2014
Event36th Annual International Conference of the IEEE Engineering in Medicince and Biology Society - Chicago, United States
Duration: 27 Aug 201430 Aug 2014

Conference

Conference36th Annual International Conference of the IEEE Engineering in Medicince and Biology Society
Country/TerritoryUnited States
CityChicago
Period27/08/1430/08/14

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