Spindle-cell B-cell lymphoma presenting in the skin

J R Goodlad

Research output: Contribution to journalArticlepeer-review

Abstract

Lymphomas with predominant spindle-cell morphology have only been previously reported in small numbers; such lesions are potentially mistaken for sarcoma or other spindle-cell tumours. We describe a 73-year-old woman who presented with a tumour on the scalp of a few months' duration. Biopsy showed a B-cell lymphoma of follicle centre cell origin with a sarcomatoid appearance and a CD20+, CD10+, CD21+, bcl-6+ immunophenotype. This case highlights the very rare occurrence of spindle-cell B-cell lymphoma presenting in the skin. An awareness of this phenomenon is essential to avoid confusion with a variety of other cutaneous spindle-cell neoplasms and to enable a correct diagnosis to be made, thereby ensuring that appropriate treatment is initiated.

Original languageEnglish
Pages (from-to)313-7
Number of pages5
JournalBritish journal of dermatology
Volume145
Issue number2
Publication statusPublished - Aug 2001

Keywords / Materials (for Non-textual outputs)

  • Aged
  • Antigens, Neoplasm
  • Diagnosis, Differential
  • Female
  • Head and Neck Neoplasms
  • Humans
  • Immunophenotyping
  • Lymphoma, B-Cell
  • Scalp
  • Skin Neoplasms
  • Treatment Outcome

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