Squamous intraepithelial neoplasia in an ovarian cyst, cervical intraepithelial neoplasia, and human papillomavirus

M J Sworn, H Jones, A T Letchworth, C S Herrington, J O McGee

Research output: Contribution to journalArticlepeer-review

Abstract

A case of squamous intraepithelial neoplasia in an ovarian cyst in association with cervical intraepithelial neoplasia (CIN) III is described. In view of the association of human papillomavirus (HPV) and CIN, the possibility that HPV infection could be associated with similar changes in the ovary was postulated. The HPV genome was shown in formalin-fixed tissue of the cervical lesion by nonisotopic in situ hybridization (NISH) and by the polymerase chain reaction (PCR). However, HPV could not be shown in the ovarian lesion by NISH or PCR. On the basis of these findings there appears to be no association between HPV infection and squamous intraepithelial neoplasia in an ovarian cyst.

Original languageEnglish
Pages (from-to)344-7
Number of pages4
JournalHuman pathology
Volume26
Issue number3
Publication statusPublished - Mar 1995

Keywords

  • Adult
  • Cervical Intraepithelial Neoplasia
  • Female
  • Humans
  • In Situ Hybridization
  • Ovarian Cysts
  • Ovarian Neoplasms
  • Papillomaviridae
  • Papillomavirus Infections
  • Polymerase Chain Reaction
  • Tumor Virus Infections
  • Uterine Cervical Neoplasms

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