Statin therapy in critical illness: an international survey of intensive care physicians’ opinions, attitudes and practice

Manu Shankar-Hari; Peter S. Kruger; Stefania Di Gangi; Damon C. Scales; Gavin D. Perkins; Danny F. McAuley; Marius Terblanche

doi:10.1186/1472-6904-12-13

Statin therapy in critical illness: an international survey of intensive care physicians’ opinions, attitudes and practice

Manu Shankar-Hari, Peter S. Kruger, Stefania Di Gangi, Damon C. Scales, Gavin D. Perkins, Danny F. McAuley, Marius Terblanche

Research output: Contribution to journal › Article › peer-review

Abstract

Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ failure. We conducted an international survey of intensive care physicians in Australia, New Zealand (ANZ) and United Kingdom (UK). The aims of the survey were to assess the current prescribing practice patterns, attitudes towards prescribing statin therapy in critically ill patients and opinions on the need for an interventional trial of statin therapy in critically ill patients.

Original language	English
Journal	BMC clinical pharmacology
Volume	12
Issue number	1
DOIs	https://doi.org/10.1186/1472-6904-12-13
Publication status	Published - 28 Jun 2012

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abstract = "Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ failure. We conducted an international survey of intensive care physicians in Australia, New Zealand (ANZ) and United Kingdom (UK). The aims of the survey were to assess the current prescribing practice patterns, attitudes towards prescribing statin therapy in critically ill patients and opinions on the need for an interventional trial of statin therapy in critically ill patients.",

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AU - Di Gangi, Stefania

AU - Scales, Damon C.

AU - Perkins, Gavin D.

AU - McAuley, Danny F.

AU - Terblanche, Marius

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AB - Pleotropic effects of statins on inflammation are hypothesised to attenuate the severity of and possibly prevent the occurrence of the host inflammatory response to pathogen and infection-related acute organ failure. We conducted an international survey of intensive care physicians in Australia, New Zealand (ANZ) and United Kingdom (UK). The aims of the survey were to assess the current prescribing practice patterns, attitudes towards prescribing statin therapy in critically ill patients and opinions on the need for an interventional trial of statin therapy in critically ill patients.

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JO - BMC clinical pharmacology

JF - BMC clinical pharmacology

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Statin therapy in critical illness: an international survey of intensive care physicians’ opinions, attitudes and practice

Abstract

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