Statistical modelling of data showing pandemic H1N1 2009 swine influenza a virus infection kinetics in vaccinated pigs

Laetitia Canini, Helen E. Everett*, Mario Aramouni, Vivien Coward, Andrew Ramsay, Michael Kelly, Sophie Morgan, Elma Tchilian, Sarah Gilbert, Bryan Charleston, Ian H. Brown, Sharon M. Brookes, Mark E.J. Woolhouse

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

A swine influenza A pandemic 2009 H1N1 (pH1N1) virus was used in a pig challenge model to investigate the efficacy of whole inactivated vaccines homologous or heterologous to the challenge virus as well as a commercial vaccine. Nasal shedding of viral RNA was monitored daily by real-time, quantitative RT-PCR (RRT-qPCR) as detailed (1). Here we report the statistical modelling of the viral RNA shedding kinetics.

Original languageEnglish
Article number104576
Number of pages6
JournalData in brief
Volume27
Early online date28 Sept 2019
DOIs
Publication statusPublished - 1 Dec 2019

Keywords / Materials (for Non-textual outputs)

  • Pandemic 2009 swine influenza a virus
  • Statistical modelling RRT-qPCR
  • Viral kinetics
  • Whole inactivated vaccine

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