Stereological estimation of the total volume of MR visible brain lesions in patients with multiple sclerosis

N ROBERTS, S BARBOSA, LD BLUMHARDT, RA KAWOSKI, RHT EDWARDS

Research output: Contribution to journalArticlepeer-review

Abstract

Point counting represents a convenient and efficient technique for estimating the area of transects through multiple sclerosis (MS) lesions on magnetic resonance (MR) images obtained for sections through the brain. When sectioning has been performed according to the Cavalieri method, unbiased estimates of the total volume of MR-visible MS plaques can be obtained with a precision of 3-5% in 5-10 min.

Original languageEnglish
Pages (from-to)375-378
Number of pages4
JournalMagnetic Resonance Materials in Physics, Biology and Medicine
Volume2
Issue number3
Publication statusPublished - Oct 1994
Event1st Nottingham Symposium on Magnetic Resonance Imaging - NOTTINGHAM, United Kingdom
Duration: 1 Jan 1994 → …

Keywords

  • MRI
  • MATHERON FORMULA
  • MULTIPLE SCLEROSIS
  • NUGGET EFFECT
  • POINT COUNTING
  • STEREOLOGY VOLUME
  • RESONANCE

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