Stereoselective synthesis of trans-beta-lactams by palladium-catalysed carbonylation of vinyl aziridines

Francesco Fontana, Gian Cesare Tron, Nekane Barbero, Serena Ferrini, Stephen P. Thomas, Varinder K. Aggarwal

Research output: Contribution to journalArticlepeer-review

Abstract

The palladium-catalysed carbonylation of vinyl aziridines can give either the trans- or cis-beta-lactam preferentially or even the delta-lactam simply by adjusting the reaction parameters ([Pd], [CO], temperature).

Original languageEnglish
Pages (from-to)267-269
Number of pages3
JournalChemical Communications
Volume46
Issue number2
DOIs
Publication statusPublished - 2010

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