Steroid regulation of menstrual bleeding and endometrial repair

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The ovarian steroid hormones progesterone and estradiol are well established regulators of human endometrial function. However, more recent evidence suggests that androgens and locally generated steroids, such as the glucocorticoids, also have a significant impact on endometrial breakdown and repair. The temporal and spatial pattern of steroid receptor presence in endometrial cells has a significant impact on the endometrial response to steroids. Furthermore, regulation of steroid receptor function by modulatory proteins further refines local responses. This review focuses on steroid regulation of endometrial function during the luteo-follicular transition with a focus on menstruation and endometrial repair.
Original languageEnglish
Pages (from-to)253-63
Number of pages11
JournalReviews in Endocrine and Metabolic Disorders
Issue number4
Publication statusPublished - 2012


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