Steroid-responsive polyradiculopathy in association with focal segmental glomerulosclerosis

Andrew R Chapman, Paul Gamble, Anne Marie Pollock, Nicola Joss

Research output: Contribution to journalLiterature reviewpeer-review

Abstract / Description of output

An 80-year-old woman presented with simultaneous increasing muscle weakness and nephrotic syndrome. A renal biopsy confirmed focal segmental glomerulosclerosis (FSGS). Her neurological diagnosis best fitted with a Guillain-Barre-like syndrome. There have been several cases of FSGS in combination with both conventional and atypical Guillain-Barre syndrome (GBS). Our patient was treated with high-dose steroids and resolution of both nephrotic syndrome and neurological symptoms occurred over 6 months. This article reviews all previously published presentations of this nature and discusses putative mechanisms for the development of concurrent FSGS and GBS.

Original languageEnglish
Pages (from-to)626-9
Number of pages4
JournalClinical kidney journal
Issue number6
Publication statusPublished - Dec 2013


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