Structure-activity relationships in beta-defensin peptides

K. Taylor, P. E. Barran, Julia Dorin

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The β-defensins comprise a large family of small cationic antimicrobial peptides widely distributed in plants, mammals and insects. These cysteine rich peptides display multifunctional properties with implications as potential therapeutic agents. Recent research has highlighted their role in both the innate and adaptive immune systems as well as being novel melanocortin ligands. Studies investigating structure and function provide an insight into the molecular basis of their immunological properties.
Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalPeptide Science
Issue number1
Publication statusPublished - Jan 2008

Keywords / Materials (for Non-textual outputs)

  • defensin
  • antimicrobial
  • structure/activity


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