Structure-based design, synthesis and characterization of the first irreversible inhibitor of Focal Adhesion Kinase

Expedite Yen-Pon; Bo Li; Marta Acebron-Garcia de Eulate; Celine Tomkieqicz-Raulet; John Dawson; Daniel Lietha; Margaret C. Frame; Xavier Coumoul; Christiane  Garbay; Melanie Etheve-Quelquejeu; Huixiong Chen

doi:10.1021/acschembio.8b00250

Structure-based design, synthesis and characterization of the first irreversible inhibitor of Focal Adhesion Kinase

Expedite Yen-Pon, Bo Li, Marta Acebron-Garcia de Eulate, Celine Tomkieqicz-Raulet, John Dawson, Daniel Lietha, Margaret C. Frame, Xavier Coumoul, Christiane Garbay, Melanie Etheve-Quelquejeu, Huixiong Chen

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	Acs chemical biology
Early online date	13 Jun 2018
DOIs	https://doi.org/10.1021/acschembio.8b00250
Publication status	E-pub ahead of print - 13 Jun 2018

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10.1021/acschembio.8b00250

E. Yen-Pon_rev 3
Published by American Chemical Society. Copyright © American Chemical Society. However, no copyright claim is made to original U.S. Government works, or works produced by employees of any Commonwealth realm Crown government in the course of their duties.
Accepted author manuscript, 5.37 MB

Margaret Frame
- Deanery of Molecular, Genetic and Population Health Sciences - Chair of Cancer Biology
- Edinburgh Cancer Research Centre
Person: Academic: Research Active

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title = "Structure-based design, synthesis and characterization of the first irreversible inhibitor of Focal Adhesion Kinase",

author = "Expedite Yen-Pon and Bo Li and {Acebron-Garcia de Eulate}, Marta and Celine Tomkieqicz-Raulet and John Dawson and Daniel Lietha and Frame, {Margaret C.} and Xavier Coumoul and Christiane Garbay and Melanie Etheve-Quelquejeu and Huixiong Chen",

year = "2018",

month = jun,

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doi = "10.1021/acschembio.8b00250",

language = "English",

journal = "Acs chemical biology",

issn = "1554-8929",

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AU - Yen-Pon, Expedite

AU - Li, Bo

AU - Acebron-Garcia de Eulate, Marta

AU - Tomkieqicz-Raulet, Celine

AU - Dawson, John

AU - Lietha, Daniel

AU - Frame, Margaret C.

AU - Coumoul, Xavier

AU - Garbay, Christiane

AU - Etheve-Quelquejeu, Melanie

AU - Chen, Huixiong

PY - 2018/6/13

Y1 - 2018/6/13

U2 - 10.1021/acschembio.8b00250

DO - 10.1021/acschembio.8b00250

M3 - Article

JO - Acs chemical biology

JF - Acs chemical biology

SN - 1554-8929

ER -

Structure-based design, synthesis and characterization of the first irreversible inhibitor of Focal Adhesion Kinase

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Margaret Frame

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