Study of Transposable Elements and Their Genomic Impact

Martin Muñoz-Lopez, Raquel Vilar-Astasio, Pablo Tristan-Ramos, Cesar Lopez-Ruiz, Jose L Garcia-Pérez

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

Abstract

Transposable elements (TEs) have been considered traditionally as junk DNA, i.e., DNA sequences that despite representing a high proportion of genomes had no evident cellular functions. However, over the last decades, it has become undeniable that not only TE-derived DNA sequences have (and had) a fundamental role during genome evolution, but also TEs have important implications in the origin and evolution of many genomic disorders. This concise review provides a brief overview of the different types of TEs that can be found in genomes, as well as a list of techniques and methods used to study their impact and mobilization. Some of these techniques will be covered in detail in this Method Book.

Original languageEnglish
Title of host publicationTransposons and Retrotransposons
PublisherSpringer
Pages1-19
Number of pages19
Volume1400
ISBN (Electronic)978-1-4939-3372-3
ISBN (Print)978-1-4939-3370-9
DOIs
Publication statusPublished - 20 Feb 2016

Publication series

NameMethods in Molecular Biology

Fingerprint

Dive into the research topics of 'Study of Transposable Elements and Their Genomic Impact'. Together they form a unique fingerprint.

Cite this