TY - CHAP
T1 - Study of Transposable Elements and Their Genomic Impact
AU - Muñoz-Lopez, Martin
AU - Vilar-Astasio, Raquel
AU - Tristan-Ramos, Pablo
AU - Lopez-Ruiz, Cesar
AU - Garcia-Pérez, Jose L
PY - 2016/2/20
Y1 - 2016/2/20
N2 - Transposable elements (TEs) have been considered traditionally as junk DNA, i.e., DNA sequences that despite representing a high proportion of genomes had no evident cellular functions. However, over the last decades, it has become undeniable that not only TE-derived DNA sequences have (and had) a fundamental role during genome evolution, but also TEs have important implications in the origin and evolution of many genomic disorders. This concise review provides a brief overview of the different types of TEs that can be found in genomes, as well as a list of techniques and methods used to study their impact and mobilization. Some of these techniques will be covered in detail in this Method Book.
AB - Transposable elements (TEs) have been considered traditionally as junk DNA, i.e., DNA sequences that despite representing a high proportion of genomes had no evident cellular functions. However, over the last decades, it has become undeniable that not only TE-derived DNA sequences have (and had) a fundamental role during genome evolution, but also TEs have important implications in the origin and evolution of many genomic disorders. This concise review provides a brief overview of the different types of TEs that can be found in genomes, as well as a list of techniques and methods used to study their impact and mobilization. Some of these techniques will be covered in detail in this Method Book.
U2 - 10.1007/978-1-4939-3372-3_1
DO - 10.1007/978-1-4939-3372-3_1
M3 - Chapter (peer-reviewed)
C2 - 26895043
SN - 978-1-4939-3370-9
VL - 1400
T3 - Methods in Molecular Biology
SP - 1
EP - 19
BT - Transposons and Retrotransposons
PB - Springer
ER -