Sub-grouping of Plasmodium falciparum 3D7 var genes based on sequence analysis of coding and non-coding regions

Thomas Lavstsen, Ali Salanti, Anja T R Jensen, David E Arnot, Thor G Theander

Research output: Contribution to journalArticlepeer-review

Abstract

The variant surface antigen family Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) is an important target for protective immunity and is implicated in the pathology of malaria through its ability to adhere to host endothelial receptors. The sequence diversity and organization of the 3D7 PfEMP1 repertoire was investigated on the basis of the complete genome sequence.
Original languageEnglish
Number of pages14
JournalMalaria Journal
Volume2
Issue number27
DOIs
Publication statusPublished - 2003

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