Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs

Sabine Tötemeyer; Pete Kaiser; Duncan J Maskell; Clare E Bryant

doi:10.1128/IAI.73.3.1873-1878.2005

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs

Sabine Tötemeyer, Pete Kaiser, Duncan J Maskell, Clare E Bryant

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S. enterica serovar Typhimurium infection. During infection, the Toll-lie receptor 1 (TLR1), TLR2, and TLR9 mRNA levels increased, while TLR6 mRNA expression decreased.

Original language	English
Pages (from-to)	1873-1878
Number of pages	6
Journal	Infection and Immunity
Volume	73
Issue number	3
DOIs	https://doi.org/10.1128/IAI.73.3.1873-1878.2005
Publication status	Published - Mar 2005

Keywords

Animals
DNA-Binding Proteins
Down-Regulation
Membrane Glycoproteins
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Organ Specificity
Receptors, Cell Surface
Salmonella Infections, Animal
Salmonella typhimurium
Toll-Like Receptor 1
Toll-Like Receptor 2
Toll-Like Receptor 6
Toll-Like Receptor 9
Toll-Like Receptors
Up-Regulation

Access to Document

10.1128/IAI.73.3.1873-1878.2005

Sublethal infection of C57BL 6 mice with Salmonella enterica Serovar Typhimurium
Copyright © 2005, American Society for Microbiology
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http://iai.asm.org/content/73/3/1873

Cite this

Tötemeyer, S., Kaiser, P., Maskell, D. J., & Bryant, C. E. (2005). Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs. Infection and Immunity, 73(3), 1873-1878. https://doi.org/10.1128/IAI.73.3.1873-1878.2005

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title = "Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs",

abstract = "Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S. enterica serovar Typhimurium infection. During infection, the Toll-lie receptor 1 (TLR1), TLR2, and TLR9 mRNA levels increased, while TLR6 mRNA expression decreased.",

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Tötemeyer, S, Kaiser, P, Maskell, DJ & Bryant, CE 2005, 'Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs', Infection and Immunity, vol. 73, no. 3, pp. 1873-1878. https://doi.org/10.1128/IAI.73.3.1873-1878.2005

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs. / Tötemeyer, Sabine; Kaiser, Pete; Maskell, Duncan J; Bryant, Clare E.

In: Infection and Immunity, Vol. 73, No. 3, 03.2005, p. 1873-1878.

Research output: Contribution to journal › Article › peer-review

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Tötemeyer S, Kaiser P, Maskell DJ, Bryant CE. Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs. Infection and Immunity. 2005 Mar;73(3):1873-1878. https://doi.org/10.1128/IAI.73.3.1873-1878.2005