Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs

Sabine Tötemeyer; Pete Kaiser; Duncan J Maskell; Clare E Bryant

doi:10.1128/IAI.73.3.1873-1878.2005

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs

Sabine Tötemeyer, Pete Kaiser, Duncan J Maskell, Clare E Bryant

Royal (Dick) School of Veterinary Studies

Research output: Contribution to journal › Article › peer-review

Abstract

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S. enterica serovar Typhimurium infection. During infection, the Toll-lie receptor 1 (TLR1), TLR2, and TLR9 mRNA levels increased, while TLR6 mRNA expression decreased.

Original language	English
Pages (from-to)	1873-1878
Number of pages	6
Journal	Infection and Immunity
Volume	73
Issue number	3
DOIs	https://doi.org/10.1128/IAI.73.3.1873-1878.2005
Publication status	Published - Mar 2005

Keywords

Animals
DNA-Binding Proteins
Down-Regulation
Membrane Glycoproteins
Mice
Mice, Inbred C3H
Mice, Inbred C57BL
Organ Specificity
Receptors, Cell Surface
Salmonella Infections, Animal
Salmonella typhimurium
Toll-Like Receptor 1
Toll-Like Receptor 2
Toll-Like Receptor 6
Toll-Like Receptor 9
Toll-Like Receptors
Up-Regulation

Access to Document

10.1128/IAI.73.3.1873-1878.2005

Sublethal infection of C57BL 6 mice with Salmonella enterica Serovar Typhimurium
Copyright © 2005, American Society for Microbiology
Final published version, 345 KB

http://iai.asm.org/content/73/3/1873

Fingerprint

Dive into the research topics of 'Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs'. Together they form a unique fingerprint.

Cite this

Tötemeyer, S., Kaiser, P., Maskell, D. J., & Bryant, C. E. (2005). Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs. Infection and Immunity, 73(3), 1873-1878. https://doi.org/10.1128/IAI.73.3.1873-1878.2005

@article{9fdee9d63e224fb4af36431a60d82263,

title = "Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs",

abstract = "Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S. enterica serovar Typhimurium infection. During infection, the Toll-lie receptor 1 (TLR1), TLR2, and TLR9 mRNA levels increased, while TLR6 mRNA expression decreased.",

keywords = "Animals, DNA-Binding Proteins, Down-Regulation, Membrane Glycoproteins, Mice, Mice, Inbred C3H, Mice, Inbred C57BL, Organ Specificity, Receptors, Cell Surface, Salmonella Infections, Animal, Salmonella typhimurium, Toll-Like Receptor 1, Toll-Like Receptor 2, Toll-Like Receptor 6, Toll-Like Receptor 9, Toll-Like Receptors, Up-Regulation",

author = "Sabine T{\"o}temeyer and Pete Kaiser and Maskell, {Duncan J} and Bryant, {Clare E}",

year = "2005",

month = mar,

doi = "10.1128/IAI.73.3.1873-1878.2005",

language = "English",

volume = "73",

pages = "1873--1878",

journal = "Infection and Immunity",

issn = "0019-9567",

publisher = "American Society for Microbiology",

number = "3",

}

Tötemeyer, S, Kaiser, P, Maskell, DJ & Bryant, CE 2005, 'Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs', Infection and Immunity, vol. 73, no. 3, pp. 1873-1878. https://doi.org/10.1128/IAI.73.3.1873-1878.2005

Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs. / Tötemeyer, Sabine; Kaiser, Pete; Maskell, Duncan J et al.

In: Infection and Immunity, Vol. 73, No. 3, 03.2005, p. 1873-1878.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs

AU - Tötemeyer, Sabine

AU - Kaiser, Pete

AU - Maskell, Duncan J

AU - Bryant, Clare E

PY - 2005/3

Y1 - 2005/3

N2 - Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S. enterica serovar Typhimurium infection. During infection, the Toll-lie receptor 1 (TLR1), TLR2, and TLR9 mRNA levels increased, while TLR6 mRNA expression decreased.

AB - Sublethal infection of C57BL/6 mice with Salmonella enterica serovar Typhimurium M525P initiates a strong inflammatory response. We measured organ expression of mRNA for Toll-like receptors and their associated signaling molecules during S. enterica serovar Typhimurium infection. During infection, the Toll-lie receptor 1 (TLR1), TLR2, and TLR9 mRNA levels increased, while TLR6 mRNA expression decreased.

KW - Animals

KW - DNA-Binding Proteins

KW - Down-Regulation

KW - Membrane Glycoproteins

KW - Mice

KW - Mice, Inbred C3H

KW - Mice, Inbred C57BL

KW - Organ Specificity

KW - Receptors, Cell Surface

KW - Salmonella Infections, Animal

KW - Salmonella typhimurium

KW - Toll-Like Receptor 1

KW - Toll-Like Receptor 2

KW - Toll-Like Receptor 6

KW - Toll-Like Receptor 9

KW - Toll-Like Receptors

KW - Up-Regulation

U2 - 10.1128/IAI.73.3.1873-1878.2005

DO - 10.1128/IAI.73.3.1873-1878.2005

M3 - Article

C2 - 15731092

VL - 73

SP - 1873

EP - 1878

JO - Infection and Immunity

JF - Infection and Immunity

SN - 0019-9567

IS - 3

ER -

Tötemeyer S, Kaiser P, Maskell DJ, Bryant CE. Sublethal infection of C57BL/6 mice with Salmonella enterica serovar typhimurium leads to an increase in levels of toll-like receptor 1 (TLR1), TLR2, and TLR9 mRNA as well as a decrease in levels of TLR6 mRNA in infected organs. Infection and Immunity. 2005 Mar;73(3):1873-1878. https://doi.org/10.1128/IAI.73.3.1873-1878.2005