Successful reintroduction of tumour necrosis factor-alpha inhibition after treatment of disseminated Lyme borreliosis

Naomi S Bulteel, Clark D Russell, Meghan R Perry, Oliver Koch

Research output: Contribution to journalArticlepeer-review

Abstract

The importance of tumour necrosis factor-alpha (TNF-α) in the human immune response to Borrelia burgdorferi is uncertain. Murine models suggest a critical role, including spirochaete reactivation following TNF-α inhibition. Our case, combined with a review of the clinical and scientific literature, provides reassurance that TNF-α inhibition can be safely reinstituted after treatment of disseminated borreliosis with standard duration antimicrobial chemotherapy.

Original languageEnglish
Pages (from-to)122-124
Number of pages3
JournalJournal of the Royal College of Physicians of Edinburgh
Volume49
Issue number2
DOIs
Publication statusPublished - Jun 2019

Fingerprint

Dive into the research topics of 'Successful reintroduction of tumour necrosis factor-alpha inhibition after treatment of disseminated Lyme borreliosis'. Together they form a unique fingerprint.

Cite this