Abstract / Description of output
A 70-year-old woman presented with symptoms of profound anaemia and evidence of intermittent gastrointestinal haemorrhage. Oesophagogastroduodenoscopy, colonoscopy, abdominal computerised tomography, sulphur colloid scintigraphy and selective mesenteric angiography were non-diagnostic. An 111indium-labelled red-cell scan was performed, which suggested bleeding from the ileum at 36 h. At laparotomy, a primary small-bowel adenocarcinoma was resected. Six weeks later, she was again anaemic. Repeat colonoscopy showed a synchronous primary colonie adenocarcinoma, which had been masked by intraluminal blood during the original 111indium scan. The lesion was impalpable, even after full mobilisation of the colon. A right hemicolectomy was performed. 111Indium has a longer half-life (67 h) than the more commonly used 99mtechnetium isotope (18 h). This allows serial imaging for up to 5 days, which may increase diagnostic efficiency in intermittent gastrointestinal bleeding. Clinicians should be aware that persisting activity from intraluminal blood may mask synchronous lesions.
Original language | English |
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Pages (from-to) | 795-799 |
Number of pages | 5 |
Journal | European Journal of Gastroenterology and Hepatology |
Volume | 16 |
Issue number | 8 |
DOIs | |
Publication status | Published - 1 Aug 2004 |
Keywords / Materials (for Non-textual outputs)
- Gastrointestinal haemorrhage
- Ileal neoplasms
- Indium radioisotopes
- Neoplasms
- Radionuclide imaging
- Second primary