SURFACE-BASED METHOD TO EVALUATE GLOBAL BRAIN SHAPE ASYMMETRIES IN HUMAN AND CHIMPANZEE BRAINS

Marc Fournier*, Benoit Combes, Neil Roberts, Simon Keller, Tim J. Crow, William D. Hopkins, Sylvain Prima

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper we use humans and chimpanzees brain MRI databases to develop methods for evaluating global brain asymmetries. We perform brain segmentation and hemispheric surface extraction on both populations. The human brain segmentation pipeline is adapted to chimpanzees in order to obtain results of good quality. To alleviate the problems due to cortical variability we propose a mesh processing algorithm to compute the brain global shape. Surface-based global brain asymmetries are computed on chimpanzee and human subjects using individual mid-sagittal plane evaluation and population-level mean shape estimation. Asymmetry results are presented in terms of axis-wise components in order to perform more specific evaluation and comparison between the two populations.

Original languageEnglish
Title of host publication2011 8TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO
Place of PublicationNEW YORK
PublisherInstitute of Electrical and Electronics Engineers (IEEE)
Pages310-316
Number of pages7
Publication statusPublished - 2011
Event8th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro - Chicago, Israel
Duration: 30 Mar 20112 Apr 2011

Publication series

NameIEEE International Symposium on Biomedical Imaging
PublisherIEEE
ISSN (Print)1945-7928

Conference

Conference8th IEEE International Symposium on Biomedical Imaging (ISBI) - From Nano to Macro
Country/TerritoryIsrael
Period30/03/112/04/11

Keywords

  • Chimps MRI brain segmentation
  • Brain global shape computation
  • Surfaced-based bilateral brain asymmetries
  • Axis-wise asymmetry components
  • Chimp and human asymmetries comparison
  • BROCAS AREA
  • ANATOMICAL ASYMMETRIES
  • STATISTICAL-ANALYSIS
  • CEREBRAL ASYMMETRY
  • PLANUM TEMPORALE
  • REGISTRATION
  • HANDEDNESS
  • HOMOLOG
  • IMAGES

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