Surface engineering of synthetic polymer materials for tissue engineering and regenerative medicine applications

Hassan Rashidi; Jing Yang; Kevin M. Shakesheff

doi:10.1039/c3bm60330j

Surface engineering of synthetic polymer materials for tissue engineering and regenerative medicine applications

Hassan Rashidi^*, Jing Yang, Kevin M. Shakesheff

^*Corresponding author for this work

Research output: Contribution to journal › Literature review › peer-review

Abstract

When using polymer materials as scaffolds for tissue engineering or regenerative medicine applications the initial, and often lasting, interaction between cells and the material are via surfaces. Surface engineering is an important strategy in materials fabrication to control and tailor cell interactions whilst preserving desirable bulk materials properties. Surface engineering methods have been described that can strongly influence cell adhesion, migration, proliferation, differentiation and functionality. This review aims to categorise the current strategies for modifying surface chemistry and/or topography in terms of the resultant change in cell behaviour.

Original language	English
Pages (from-to)	1318-1331
Number of pages	14
Journal	Biomaterials science
Volume	2
Issue number	10
DOIs	https://doi.org/10.1039/c3bm60330j
Publication status	Published - 2014

Keywords

MESENCHYMAL STEM-CELLS
POLYSTYRENE-BLOCK-POLY(TERT-BUTYL ACRYLATE) FILMS
NEURAL PROGENITOR CELLS
OSTEOBLAST-LIKE CELLS
IN-VITRO
SUBSTRATE NANOTOPOGRAPHY
ELECTROSPUN NANOFIBERS
EXTRACELLULAR-MATRIX
BIOLOGICAL ANALYSIS
POLY(LACTIC ACID)

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title = "Surface engineering of synthetic polymer materials for tissue engineering and regenerative medicine applications",

abstract = "When using polymer materials as scaffolds for tissue engineering or regenerative medicine applications the initial, and often lasting, interaction between cells and the material are via surfaces. Surface engineering is an important strategy in materials fabrication to control and tailor cell interactions whilst preserving desirable bulk materials properties. Surface engineering methods have been described that can strongly influence cell adhesion, migration, proliferation, differentiation and functionality. This review aims to categorise the current strategies for modifying surface chemistry and/or topography in terms of the resultant change in cell behaviour.",

keywords = "MESENCHYMAL STEM-CELLS, POLYSTYRENE-BLOCK-POLY(TERT-BUTYL ACRYLATE) FILMS, NEURAL PROGENITOR CELLS, OSTEOBLAST-LIKE CELLS, IN-VITRO, SUBSTRATE NANOTOPOGRAPHY, ELECTROSPUN NANOFIBERS, EXTRACELLULAR-MATRIX, BIOLOGICAL ANALYSIS, POLY(LACTIC ACID)",

author = "Hassan Rashidi and Jing Yang and Shakesheff, {Kevin M.}",

year = "2014",

doi = "10.1039/c3bm60330j",

language = "English",

volume = "2",

pages = "1318--1331",

journal = "Biomaterials science",

issn = "2047-4830",

publisher = "Royal Society of Chemistry",

number = "10",

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TY - JOUR

T1 - Surface engineering of synthetic polymer materials for tissue engineering and regenerative medicine applications

AU - Rashidi, Hassan

AU - Yang, Jing

AU - Shakesheff, Kevin M.

PY - 2014

Y1 - 2014

N2 - When using polymer materials as scaffolds for tissue engineering or regenerative medicine applications the initial, and often lasting, interaction between cells and the material are via surfaces. Surface engineering is an important strategy in materials fabrication to control and tailor cell interactions whilst preserving desirable bulk materials properties. Surface engineering methods have been described that can strongly influence cell adhesion, migration, proliferation, differentiation and functionality. This review aims to categorise the current strategies for modifying surface chemistry and/or topography in terms of the resultant change in cell behaviour.

AB - When using polymer materials as scaffolds for tissue engineering or regenerative medicine applications the initial, and often lasting, interaction between cells and the material are via surfaces. Surface engineering is an important strategy in materials fabrication to control and tailor cell interactions whilst preserving desirable bulk materials properties. Surface engineering methods have been described that can strongly influence cell adhesion, migration, proliferation, differentiation and functionality. This review aims to categorise the current strategies for modifying surface chemistry and/or topography in terms of the resultant change in cell behaviour.

KW - MESENCHYMAL STEM-CELLS

KW - POLYSTYRENE-BLOCK-POLY(TERT-BUTYL ACRYLATE) FILMS

KW - NEURAL PROGENITOR CELLS

KW - OSTEOBLAST-LIKE CELLS

KW - IN-VITRO

KW - SUBSTRATE NANOTOPOGRAPHY

KW - ELECTROSPUN NANOFIBERS

KW - EXTRACELLULAR-MATRIX

KW - BIOLOGICAL ANALYSIS

KW - POLY(LACTIC ACID)

U2 - 10.1039/c3bm60330j

DO - 10.1039/c3bm60330j

M3 - Literature review

VL - 2

SP - 1318

EP - 1331

JO - Biomaterials science

JF - Biomaterials science

SN - 2047-4830

IS - 10

ER -

Surface engineering of synthetic polymer materials for tissue engineering and regenerative medicine applications

Abstract

Keywords

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