Switching Pathways: Room-Temperature Neutral Solvolysis and Substitution of Amides

Marc Hutchby, Chris E. Houlden, Mairi F. Haddow, Simon N. G. Tyler, Guy C. Lloyd-Jones*, Kevin I. Booker-Milburn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Original languageEnglish
Pages (from-to)548-551
Number of pages4
JournalAngewandte Chemie International Edition
Volume51
Issue number2
DOIs
Publication statusPublished - 2012

Keywords

  • amides
  • solvolysis
  • steric hindrance
  • substituent effects
  • substitution
  • ACYL TRANSFER-REACTIONS
  • N-ARYL-LACTAMS
  • TWISTED AMIDE
  • DISTORTED AMIDES
  • PEPTIDE-BOND
  • HYDROLYSIS
  • KINETICS
  • PURIFICATION
  • MECHANISM
  • RESONANCE

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