Synthesis of a novel tetrafluoropyridine-containing amino acid and tripeptide

Alex S. Hudson, Alex Hoose, Christopher R. Coxon, Graham Sandford, Steven L. Cobb*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The synthesis of a novel fluoropyridine-containing amino acid from pentafluoropyridine by a nucleophilic substitution process is reported. The orthogonal protecting groups can be manipulated and the fluoropyridine amino acid incorporated into a tripeptide.

Original languageEnglish
Pages (from-to)4865-4867
Number of pages3
JournalTetrahedron Letters
Volume54
Issue number36
DOIs
Publication statusE-pub ahead of print - 8 Jul 2013

Keywords / Materials (for Non-textual outputs)

  • Novel amino acid
  • Pentafluoropyridine
  • Peptides

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