Synthesis of DBpin using Earth-abundant metal catalysis

Andrew W.m. Cummins, Shuyang Li, Dominic R. Willcox, Tommi Muilu, Jamie H. Docherty, Stephen P. Thomas

Research output: Contribution to journalArticlepeer-review

Abstract / Description of output

The synthesis of DBpin was achieved using (EtBIP)CoCl2 or (tBuPNN)FeCl2 as pre-catalysts activated with NaOtBu. (EtBIP)CoCl2 was used as a pre-catalyst for the hydrogen isotope exchange of HBpin with D2, and (tBuPNN)FeCl2 for deuterogenolysis of B2pin2. The one-pot, tandem hydrogenolysis-hydroboration/deuterogenolysis-deuteroboration reaction of terminal alkenes could be catalysed by (tBuPNN)FeCl2 to give alkyl boronic esters.
Original languageEnglish
Pages (from-to)131084
JournalTetrahedron
Early online date29 Feb 2020
DOIs
Publication statusE-pub ahead of print - 29 Feb 2020

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