Systematic determination of the mosaic structure of bacterial genomes: species backbone versus strain-specific loops

H Chiapello, I Bourgait, F Sourivong, G Heuclin, A Gendrault-Jacquemard, M-A Petit, M El Karoui

Research output: Contribution to journal › Article › peer-review

Abstract

Public databases now contain multitude of complete bacterial genomes, including several genomes of the same species. The available data offers new opportunities to address questions about bacterial genome evolution, a task that requires reliable fine comparison data of closely related genomes. Recent analyses have shown, using pairwise whole genome alignments, that it is possible to segment bacterial genomes into a common conserved backbone and strain-specific sequences called loops.
Original languageEnglish
Article number171
Number of pages10
JournalBMC Bioinformatics
Volume6
DOIs
Publication statusPublished - 2005

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