Systematic review of therapeutic interventions in human prion disease

Lesley A Stewart; Larysa H M Rydzewska; Geraldine F Keogh; Richard S G Knight

doi:10.1212/01.wnl.0000308955.25760.c2

Systematic review of therapeutic interventions in human prion disease

Lesley A Stewart, Larysa H M Rydzewska, Geraldine F Keogh, Richard S G Knight

Research output: Contribution to journal › Article › peer-review

Abstract

The potential threat of a large outbreak of variant Creutzfeldt-Jakob disease initiated a proliferation of research into the understanding and treatment of human prion disease. However, clinical research is at an early stage with a pressing need for objective evaluation of treatments to inform the design of future studies.

Original language	English
Pages (from-to)	1272-81
Number of pages	10
Journal	Neurology
Volume	70
Issue number	15
DOIs	https://doi.org/10.1212/01.wnl.0000308955.25760.c2
Publication status	Published - 2008

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title = "Systematic review of therapeutic interventions in human prion disease",

abstract = "The potential threat of a large outbreak of variant Creutzfeldt-Jakob disease initiated a proliferation of research into the understanding and treatment of human prion disease. However, clinical research is at an early stage with a pressing need for objective evaluation of treatments to inform the design of future studies.",

author = "Stewart, {Lesley A} and Rydzewska, {Larysa H M} and Keogh, {Geraldine F} and Knight, {Richard S G}",

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AU - Stewart, Lesley A

AU - Rydzewska, Larysa H M

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AU - Knight, Richard S G

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AB - The potential threat of a large outbreak of variant Creutzfeldt-Jakob disease initiated a proliferation of research into the understanding and treatment of human prion disease. However, clinical research is at an early stage with a pressing need for objective evaluation of treatments to inform the design of future studies.

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DO - 10.1212/01.wnl.0000308955.25760.c2

M3 - Article

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VL - 70

SP - 1272

EP - 1281

JO - Neurology

JF - Neurology

SN - 0028-3878

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