Original language | English |
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Journal | Modern Pathology |
Publication status | Published - 21 Jun 2022 |
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In: Modern Pathology, 21.06.2022.
Research output: Contribution to journal › Article › peer-review
TY - JOUR
T1 - Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: A multi-operator and multi-institutional study
AU - The International Ki67 in Breast Cancer Working Group of the Breast International Group & North American Breast Cancer Group (BIG-NABCG)
AU - Acs, Balazs
AU - C.Y. Leung, Samuel
AU - M. Kidwell, Kelley
AU - Arun, Indu
AU - Augulis, Renaldas
AU - S Badve, Sunil
AU - Bai, Yalai
AU - L Bane, Anita
AU - Bartlett, John
AU - Bayani, Jane
AU - Bigras, Gilbert
AU - Blank, Annika
AU - Buikema, Henk
AU - C. Chang, Martin
AU - L. Dietz, Robin
AU - Dodson, Andrew
AU - Fineberg, Susan
AU - M. Focke, Cornelia
AU - Gao, Dongxia
AU - M. Gown, Allen
AU - Gutierrez, Carolina
AU - Hartman, Johan
AU - Kos, Zuzana
AU - Laenkholm, Anne-Vibeke
AU - Laurinavicius, Arvydas
AU - M. Levenson, Richard
AU - Mahboubi-Ardakani, Rustin
AU - G. Mastropasqua, Mauro
AU - Nofech-Mozes, Sharon
AU - C Osborne, Kent
AU - M Penault-Llorca, Frederique
AU - Piper, Tammy
AU - Quintayo, Mary-Anne
AU - T Rau, Tilman
AU - Reinhard, Stefan
AU - Robertson, Stephanie
AU - Salgado, Roberto
AU - Sugie, Tomoharu
AU - van der Vegt, Bert
AU - Viale, Giuseppe
AU - A. Zabaglo, Lila
AU - F. Hayes, Daniel
AU - Dowsett, Mitch
AU - O Nielson, Torsten
AU - L Rimm, David
N1 - Funding Information: BA is supported by The Swedish Society for Medical Research (Svenska Sällskapet för Medicinsk Forskning) Postdoctoral grant, Swedish Breast Cancer Association (Bröstcancerförbundet) Research grant 2021, The Fulbright Program and The Rosztoczy Foundation Scholarship Program. MD, DFH, RS (BCRF grant N° 17–194), (many others) and DLR are supported by the Breast Cancer Research Foundation. This work was supported by a generous grant from the Breast Cancer Research Foundation (DFH). Additional funding for the UK laboratories was received from Breakthrough Breast Cancer and the National Institute for Health Research Biomedical Research Centre at the Royal Marsden Hospital. Funding for the Ontario Institute for Cancer Research is provided by the Government of Ontario. JH is the Lilian McCullough Chair in Breast Cancer Surgery Research and the CBCF Prairies/NWT Chapter. Open access funding provided by Karolinska Institute. Funding Information: In the last 12 months, DLR has served as a consultant for advisor to Astra Zeneca, Agendia, Amgen, Cell Signaling Technology, Cepheid, Danaher, Konica-Minolta, Merck, PAIGE.AI, Regeneron, and Sanofi. TON reports a proprietary interest in PAM50/Prosigna and consultant work with Veracyte. JH was former member of the advisory board at Visiopharm A/S. JH has obtained speaker’s honoraria or advisory board remunerations from Roche, Novartis, AstraZeneca, Eli Lilly, Pfizer and MSD. JH is co-founder and shareholder of Stratipath AB. JH has received institutional research grants from Cepheid and Novartis. DFH reports no research or personal financial support related to this study. DFH does report research support unrelated to this study provided to his institution during conduct from Menarini/Silicon BioSystems, Astra Zeneca, Eli Lilly Company, Merrimack Pharmaceuticals, Inc. (Parexel Intl Corp), Veridex and Janssen Diagnostics (Johnson & Johnson), Pfizer, and Puma Biotechnology, Inc. (subcontract Wash Univ St. Louis to Univ Mich). DFH also reports that his institution holds a patent regarding circulating tumor cell characterization for which DFH is the named investigator that was licensed to Menarini Silicon Biosystems and from which both received annual royalties, ending in January 2021. DFH reports personal income related to consulting or advisory board activities from BioVeca, Cellworks, Cepheid, EPIC Sciences, Freenome, Guardant, L-Nutra, Oncocyte, Macrogenics, Predictus BioSciences, Salutogenic Innovations, Turnstone Biologics, and Tempus. DFH reports personally held stock options from InBiomotion. BvdV reports speaker’s honoraria or consultation/advisory board remunerations provided to his institution from Visiopharm, Philips, Merck/MSD and Diaceutics. GV reports receipt of grants/research supports from Roche/Genentech, Ventana Medical Systems, Dako/Agilent Technologies, and receipt of honoraria or consultation fees from Ventana, Dako/Agilent, Roche, MSD Oncology, AstraZeneca, Daiichi Sankyo, Pfizer, Eli Lilly. ZK has served in a paid advisory role to Eli Lilly. Unrelated to this study, SR is currently employed by Stratipath AB. RS reports non-financial support from Merck and Bristol Myers Squibb; research support from Merck, Puma Biotechnology, and Roche; and advisory board fees for Bristol Myers Squibb; and personal fees from Roche for an advisory board related to a trial-research project. RS has no COI related to this project. SF served as expert pathology consultant for Axdev Global Corp inc and as an expert advisory panel for Genomic Health in 2017. RML is co-founder and shareholder of MUSE Microscopy, Inc. and Histolix, Inc. RML served as consultant for Cell IDx, Inc., BriteSeed, Inc., ImmunoPhotonics, Inc., Pathology Watch, Inc. and Verily, Inc. FPL reports board meetings and conference support from Astrazeneca, Lilly, Novartis, Pfizer and Roche. JB served as consultant for Insight Genetics, Inc., BioNTech AG, Biotheranostics, Inc., Pfizer, Rna Diagnostics Inc., oncoXchange/MedcomXchange Communications Inc, Herbert Smith French Solicitors, OncoCyte Corporation. JB served as member of the scientific advisory board for MedcomXchange Communications Inc. JB reports honoraria from NanoString Technologies, Inc., Oncology Education, Biotheranostics, Inc., MedcomXchange Communications Inc. JB reports travel and accommodation expenses support from Biotheranostics, Inc., NanoString Technologies, Inc., Breast Cancer Society of Canada. JB received research funding from Thermo Fisher Scientific, Genoptix, Agendia, NanoString Technologies, Inc., Stratifyer GmbH, Biotheranostics, Inc. The remaining authors declare no competing interests. Publisher Copyright: © 2022, The Author(s).
PY - 2022/6/21
Y1 - 2022/6/21
M3 - Article
SN - 0893-3952
JO - Modern Pathology
JF - Modern Pathology
ER -