Prion infections in the central nervous system (CNS) can cause extensive neurodegeneration. Systemic inflammation can affect the progression of some neurodegenerative disorders. The gastrointestinal helminth pathogen Trichuris muris was used to stimulate a chronic systemic inflammation, characterised by T helper cell type 1-polarized and high serum Interferon gamma (IFNγ) responses, to determine the impact on prion disease progression and neuropathology.
|Publication status||Published - 11 Mar 2020|
|Event||Edinburgh Neuroscience day 2020 - |
Duration: 11 Mar 2020 → 11 Mar 2020
|Conference||Edinburgh Neuroscience day 2020|
|Abbreviated title||Neuroscience Day 2020|
|Period||11/03/20 → 11/03/20|
- Trichuris muris